| Pancreatic Pathology Online
Pathology of Serous Cystic Tumours of the Pancreas
Dr Sampurna Roy MD June 2016
Syn: Serous Cystadenoma; Microcystic Adenoma or Cystadenoma ; Glycogen-Rich Cystadenoma.
Cystic tumours of the pancreas are formed by serous or mucinous structures showing all stages of cellular differentiation.
According to the WHO classification, they can be subdivided on the basis of their histological type and biological behavior into benign tumors, borderline tumors, and malignant tumours.
Serous Cystadenoma can be found at any site in the pancreas and occurs more frequently in women.
These tumours are always benign.
It is often an incidental finding on abdominal scans or at autopsy but can present with symptoms and signs of expansile abdominal mass or cause obstruction, example of the common bile duct.
Multifocal examples of this tumor has been reported.
The lesions tend to be relatively large (6-8 cms) and on cut section often show a central stellate scar with a myriad of small surrounding cysts.
Less commonly the cysts are much fewer and larger and these can cause diagnostic confusion at operation.
Whatever the gross appearance, the histological findings are uniform.
The cystic spaces are lined by clear cuboidal cells which can be shown to contain glycogen.
Rarely, the tumours are associated with :
(i) Extra-pancreatic malignant tumours ;
(ii) Hepatic or renal cysts;
(iii) Diabetes mellitus.
Malignant change and metastases are extremely rare.
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