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Retinal tumors of the adult--two case reports.Oftalmologia.
2004;48(2):37-41.
Most frequently,
retinal tumors that affect adults are rare, benign lesions that arise
from vascular structures (hemangioma), neuroglial structures (astrocytoma,
massive gliosis of the retina) or neuroepithelial cells (occasional
forms of retinoblastoma that spontaneously stop growing and do not
achieve or lose their malignant character). Retinal metastasis might
be encountered but the settling of cancer cells at this level is very
rare. Retinal tumors have frequently systemic associations and in this
case they are included in the phacomatoses syndrome; nevertheless,
they can also occur as a nonsyndromic pathological disorder. Even if
the incidence is rare and the variety limited, issuing a diagnosis
proves difficult because retinal tumors look like other lesions or due
to a low visibility of the ocular fundus. Hereunder we shall present
you two cases of retinal tumors that were difficulty diagnosed and
treated by surgical excision of the tumor.
Appearance
and rapid growth of retinal tumor (reactive astrocytic
hyperplasia?).Graefes
Arch Clin Exp Ophthalmol. 1999
Jan;237(1):78-81
BACKGROUND:
Tumors of the retina are often seen in association with systemic
syndromes such as neurofibromatosis, tuberous sclerosis, and von
Hippel-Lindau disease. These masses are either astrocytic hamartomas
or capillary hemangiomas. Retinal tumors unassociated with other
systemic disease have also been reported. METHODS: The
ophthalmologic evaluation and clinical course of a 65-year-old woman
who developed an epiretinal membrane followed by a vascularized
retinal mass in the macular area are described. RESULTS: Appearance
and rapid growth of the lesion were documented with fundus
photography and fluorescein angiography. The lesion was treated with
photocoagulation following growth that threatened the foveal region.
Choroidal neovascularization subsequently developed toward the
fovea, and visual acuity has remained poor. After 4 years of
follow-up no local recurrence or systemic disease possibly related
to the tumor has occurred. CONCLUSIONS: This is the first report of
documented appearance and rapid growth of a retinal tumor that
resembles a reactive astrocytic hyperplasia.
[Retinoblastoma update--management and classification (Part I)]Klin
Oczna. 2006;108(4-6):253-7.
The aim of
this paper is to present updated data on diagnosis, management and
classification of retinoblastoma. The authors describe the growth
patterns of retinoblastoma including the diffuse infiltrating type,
the features of spontaneously regressed and spontaneously arrested
retinoblastoma. In addition, retinoblastoma genetics including 13 q
deletion syndrome, are discussed. Finally, they present the
International Intraocular Retinoblastoma Classification (IIRC) and
make recommendations regarding chemotherapy after enucleation based
on histopathology findings.
[Retinoblastoma
update--therapy (Part II)]Klin
Oczna. 2006;108(4-6):258-62.
The aim of
this paper is to present updated data on the treatment of
retinoblastoma. The authors describe current management based on the
International Intraocular Retinoblastoma Classification (IIRC). They
discuss the different methods of treatment, including chemoreduction,
subconjunctival carboplatin, transpupillar thermotherapy,
cryotherapy, laser photocoagulation, episcleral plaque radiotherapy,
external-beem radiotherapy and enucleation.
Retinal tumours in
neurofibromatosis.Can
J Ophthalmol. 1977;12(1):68-70.
A 45-year-old
male with von Recklinghausen's disease was noted to have hamartomatous
lesions of the retinae similar to those more commonly described in
Bourneville's disease and von Hippel-Lindau's disease. These findings
would appear to support the concept that the retinal changes in
neurofibromatosis occupy an intermediate position between those seen
in the other two phakomatoses.
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