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                 Myxoid Tumours of Soft Tissue

 
November 2009
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The effect of mechanical trauma is related to the force transmitted to the tissue, the rate at which the transfer occurs, the surface area to which the force is transferred, and the area of the body that is injured.  The disruption of the continuity of the tissue results in a wound. The transmission of the energy absorbed can produce alterations elsewhere in the body.

Force expended:

The amount of energy released is related to the velocity and mass of the object that strikes the person, or to that of the person who collides with a stationary object.

In addition to the lateral displacement, many objects that strike people - from bullets to car wheels - have rotational forces.

Prolongation of the period of impact dissipates some of the energy, as when a boxer "rolls with a punch".

Transfer area:

The area over which transfer of force occurs is particularly important.

The intensity - that is, the force exerted per unit area - decreases with the increasing area.

A protective helmet does not lessen the force of a blow or projectile, but diffuses it over a large area.

Body area:

The area of the body that is affected by physical trauma plays an important role.

The compressibility of the tissue adjacent to the transmitted force in parts determines its effect.

A blow over a large muscle mass, such as the thigh or upper arm, is often less injurious than a direct blow to a poorly shielded bone, such as the anterior tibia.  Furthermore, the distribution of the force is important.

Blows over a hollow viscus can rupture the organ because of compression of the fluid or gas it contains - organs located beneath the skin, like the liver, can be easily ruptured.

An impact directly over the heart can even disturb its electrical systems.

Contusions:

A force with sufficient energy may disrupt capillaries and venules within an organ by physical means alone.

If this occurs in the skin, a loss of blood into the tissue space occurs.

The resultant altered coloration identifies a contusion, namely, a localized area of mechanical injury with local hemorrhage.

The change may be so limited that the only histologic change is hemorrhage in tissue spaces outside of the vascular compartment.

The presence of a discrete blood pool within the tissue is termed hematoma.

Initially the deoxygenated blood renders the area blue to blue-black, as in the classic "black eye".

Macrophages ingest the red blood cells and convert the hemoglobin to bilirubin, thus changing the colour from blue to yellow.

Both mobilization of the pigment by macrophages and further metabolism of bilirubin cause the yellow to fade to yellowish green and then to disappear.

Abrasions:

A direct or tangential impact can crush or scrape the epithelial surface of the skin, producing a defect called abrasion.

The disruptive force may destroy some of the cells by crushing them, and thus may provide a portal of entry for microorganisms.

There may be disruption of the epidermis itself, and there may also be vascular distortion of the cells within the dermis.

The impact of the agent and its configuration are frequently seen in these wounds, and are of special interest to the forensic pathologist.

Lacerations:

Should the force be greater, and should the tangential impact be stronger, the epithelium can split and tear, resulting in a laceration.

Lacerations are usually the result of unidirectional displacement, but they may have crushed margins, in which case they are termed abraded lacerations.

Incisions:

 

The deliberate opening of the skin by a cutting instrument, usually the surgeon's scalpel, is an incision.

 

Incisions have particularly sharp edges and spare no tissue to the depth of the wound.

 

Deep penetrating wounds produced by high-velocity projectiles, such as bullets, are often deceptive because the energy of the missile as it passes through the body may be released at sites distant from the space itself.

 

Bullets, because they rotate, produce a well-defined and usually round entrance wound.

 

Once the projectile enters the flesh, however, it may fragment, tumble, or actually explode, resulting in a remarkable degree of tissue damage and a large, ragged exit wound.

                       

Low incidence of multiple organ failure after major trauma.Injury. 2007 Jun 15;

BACKGROUND: In major trauma patients, multiple organ failure (MOF) is considered a leading cause of death. Acute lung injury is deemed a "pacemaker" of MOF. The purpose of this study was to determine if incidence of organ failure and mortality in multiple trauma patients can be reduced by implementation of lung-protective strategies. METHODS: All critically ill multiple trauma patients admitted to the ICU of a major trauma center in Berlin, Germany from January 1999 to December 2002 were analyzed retrospectively. Patients were ventilated pressure controlled with low tidal volumes and adequate PEEP. RESULTS: n=287 patients were included. The most frequent injuries were traumatic brain injury (TBI-68%), chest trauma (68%), and lung contusions (55%). Injury severity score (ISS) was 32+/-19 (mean+/-standard deviation), polytraumaschluessel (PTS) 34+/-19, and APACHE II 14+/-7. During their ICU-stay 16 patients died, 9 (56%) from TBI. Single-organ-failure occurred in n=69 patients (24%, mortality 5%), two-organ-failure in n=22 (8%, mortality 14%), and MOF in n=9 (3%, mortality 13%); one patient died from MOF 14 days after trauma. The number of days on mechanical ventilation increased depending on the number of organs failed (R=0.618, p<0.001). Seven patients (2%) fulfilled ARDS criteria for longer than 24h despite optimized ventilatory settings, one died of irreversible shock. Patients with MOF had a significantly increased ICU-LOS (35+/-15 days) compared to patients without organ failure (11+/-11 days; p<0.001). CONCLUSION: The low incidence of MOF in our series of trauma patients suggests that MOF may be prevented in some patients by implementation of lung-protective strategies. The improved outcome was associated with an increased ICU-LOS.

Penetrating abdominal trauma.Cir Cir. 2006 Nov-Dec;74(6):431-42.

BACKGROUND: The abdomen ranks in third place of body areas injured by trauma. Evaluation and stabilization of these patients form the cornerstone in emergency medicine. Diagnostic approach and treatment outcome are influenced by several factors. Injury mechanism and pattern vary according to geography and there is an association with drugs and alcohol. Physical examination remains the most reliable indicator for surgery. Associated injuries are present in up to 26% of cases. We undertook this study to determine penetrating abdominal trauma incidence and frequency, demographic factors, rate of immediate and delayed laparotomies, and associated complications as well as to define the usefulness of penetrating abdominal trauma index (PATI). METHODS: An observational, prospective, longitudinal descriptive study was carried out at the Hospital Central "Ignacio Morones Prieto," San Luis Potosi, Mexico from January 1, 2005 to December 31, 2005 on patients who underwent exploratory laparotomy for penetrating abdominal trauma. Twenty one variables were studied. Basic statistical analysis, ANOVA, chi(2) and Student's t-test were used. RESULTS: Of the 79 patients who were included, 93.67% were males. The third decade of life was the most affected, with a night presentation being predominant as a result of personal violence. Drug use was observed in 50.6%; stab wounds in 63.3%. The most frequent locations were the left upper and right lower quadrants and epigastrium; solitary wounds were predominant. Associated injuries were most common in the thorax and limbs. Of the laparotomies performed, 92.4% were urgent and 60.53% were therapeutic; 15.19% required reoperations; complications were observed in 39.24%; and mortality rate was 3.9%. CONCLUSIONS: Due to high non-therapeutic and negative laparotomies rates, a more selective approach is needed, including repetitive physical examination and the appropriate use of auxiliary diagnostic studies.

                   

 

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