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Pancreatic benign schwannoma treated by simple
enucleation: case report and review of literature.Pancreas.
2005 Oct;31(3):286-8.
Benign
schwannoma in the pancreatic head is very rare, with only 11
patients being reported in the English literature from a Medline
search. Furthermore, only 1 of them was treated by simple
enucleation. Herein, we present another enucleation case: a
71-year-old male patient with a 1.5 x 1.2-cm low-density mass,
mimicking a cystic lesion located at the head of pancreas, which was
detected by computed tomography. This tumor failed to be discovered
by abdominal ultrasound. At laparotomy, a solid mass 1 cm in
diameter was identified; it was the smallest one in the pancreatic
head according to the 11 previous reported cases. No complications
were found after the operation. At 10-month follow-up, the patient
remains asymptomatic and has no signs of recurrence. The data of the
12 patients indicated that simple minimal invasive enucleation for
small benign schwannoma in the pancreatic head was feasible and
safe; early detection and early treatment of the tumor were helpful
in increasing the ratio of enucleation and avoiding a very invasive
Whipple operation.
Pancreatic schwannoma. A case report and review of the literature.JOP.
2004 Nov 10;5(6):520-6.
CONTEXT:
Pancreatic schwannomas are rare neoplasms. These tumors vary in size
and two thirds are partially cystic which grossly mimic pancreatic
cystic lesions. Computed tomography and magnetic resonance imaging
are the primary initial imaging modalities. Definitive diagnosis is
typically made at the time of laparotomy following biopsy. Surgical
resection is the mainstay of treatment. CASE REPORT: A 69-year-old
woman presented with abdominal pain in the epigastric and left upper
quadrant. The patient had no systemic symptom and laboratory results
including tumor markers were negative. A CT scan of the abdomen
showed a 5 cm mass arising from the head of the pancreas. Needle
biopsy revealed a mass consistent with schwannoma. At laparotomy, a
large pancreatic head mass was found to encase the superior
mesenteric artery, and portal vein confluence. Frozen biopsy showed
schwannoma. Curative resection was deferred due to extensive
vascular involvement and favorable tumor biology. A
gastrojejunostomy was performed and radiation therapy was instituted
post-operatively. CONCLUSIONS: Only 24 cases of pancreatic
schwannoma had been previously reported. Definitive diagnosis is
obtained with routine histology. Most tumors are benign and surgical
resection is curative. The role of radiation therapy in the
management of unresectable tumors is still unclear.
Cystic schwannoma of the pancreas.Ann
Diagn Pathol. 2003;7(5):285-91.
Intrapancreatic schwannoma is a rare neoplasm. We report a case of a
46-year-old man with a cystic schwannoma in the head of the
pancreas. This tumor, based on clinical manifestations and
radiologic features, was initially suspected to be a cystic mucinous
tumor of the pancreas or a pseudocyst. Histologically, the tumor was
a typical schwannoma with cyst formation caused by degenerative
changes. Immunostaining showed the tumor cells to be strongly and
diffusely positive for S-100 protein, vimentin, and CD56, and
negative for cytokeratin AE1/AE3, desmin, smooth muscle myosin
specific, CD34, and CD117, which support the diagnosis of schwannoma.
Cystic schwannoma is a rare neoplasm occurring in the pancreas and
should be considered in the differential diagnoses for patients
presenting with pancreatic cystic lesions.
Schwannoma of the
pancreas: a report of two cases and a review of the literature.Mod
Pathol. 1998 Dec;11(12):1178-82.
Schwannoma
of the pancreas is a rare neoplasm. It generally affects older
adults (average age, 60 yr). The sex incidence is equal. These
tumors vary considerably in size and approximately two-thirds are
partially cystic, which can cause clinical confusion with epithelial
neoplasms. Histologically, they are typical schwannomas, with Antoni
A and Antoni B areas, and they do not cause undue diagnostic
problems once adequate tissue is examined histologically.
Benign
retroperitoneal schwannoma mimicking a pancreatic cystic tumor: case
report and literature review.Hepatogastroenterology.
1998 Nov-Dec;45(24):2418-20.
A rare case
of benign retroperitoneal schwannoma mimicking a pancreatic cystic
tumor is reported herein. The tumor mass, based on a computed
tomography scan and an abdominal echo examination, was initially
suspected to be a mucinous cystadenoma or cystadenocarcinoma of the
pancreas. However, the surgical and pathohistological findings made
a final diagnosis of benign pancreatic schwannoma. The patient is
doing well at a 2-year follow-up. The tumor, 18x17x15 cm in size,
represented the largest among reported pancreatic schwannomas.
Furthermore, a comprehensive review of reported cases of pancreatic
schwannoma was carried out to summarize corresponding findings,
including benign or malignant forms, adherence to other tissues,
cystic change of the tumor, as well as relation to von
Recklinghausen's neurofibromatosis.
The schwannoma: an
uncommon type of cystic lesion of the pancreas.
Ital J Gastroenterol. 1993 Aug-Sep;25(7):385-7.
Schwannomas
of the pancreas are rare and their number is lower than is usually
reported in the literature since some were probably neurofibromas.
We report a further case characterized by cystic feature, clinically
mimicking a pancreatic pseudocyst.Cystic lesions of the pancreas
also comprise the schwannomas, both benign or malignant, as has been
previously reported and is stressed by the present case. Cyst
formation characterizes many diseases of the pancreas, both
neoplastic and not. Difficulties in the differential diagnosis of
cysts are fortunately reduced by the preponderance of pseudocysts
(i.e. non-neoplastic cysts) and, among neoplastic ones, of
cystadenomas and cystadenocarcinomas. As a consequence, uncommon
cystic neoplasms are neglected and very often misdiagnosed. We
reported a case of solitary schwannoma mimicking a pancreatic
pseudocyst, interesting both because of its rarity and because of
its cystic feature which was previously reported in the literature
but not emphasized.
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