Pancreatic Pathology Online

Paediatric Pancreatic Tumours

Dr Sampurna Roy MD            July 2016

 

Pancreatic exocrine tumours in infants and children are rare.

The major problem for the clinician is a lack of experience and of accepted therapeutic strategies.

Malignant pancreatic tumours in children show a pattern different from that in adults.

In infants, especially pancreatoblastomas, solid cystic tumours of females, and endocrine carcinomas of the pancreas must be expected.

In addition acinar cell carcinoma can also occur.

Ductal adenocarcinoma is virtually absent.

 

Pancreatoblastoma

Solid Pseudopapillary Tumour

Pancreatoblastomas and solid cystic tumors are mainly found in the head of the pancreas.

Fibrotic capsules with rare, late metastases are characteristics of these tumors, indicating total resection to be an important therapeutic procedure.

Pancreatoblastomas should additionally be treated with chemotherapy.

Endocrine carcinomas of the pancreas (malignant gastrinomas and malignant insulinomas) should also primarily be treated with radical surgery, including extensive lymph node dissection.

In case of distant metastases, local resection (liver) or somatostatin in combination with chemotherapy (streptozocin in the case of malignant insulinomas) may be used.

 

Five interesting Pancreatic Tumours.

Follow the links:

- Pancreatoblastoma

- Solid Pseudopapillary Tumour of the Pancreas

- Acinar cell carcinoma

- Pancreatic Insulinomas

- Pancreatic Gastrinoma

 

Further reading:

Pancreatic tumors in children: radiologic-pathologic correlation.

Laparoscopic distal pancreatectomy in children: case report and review of the literature.

Pancreatic tumors in children: report of three cases.

A 20-year review of pediatric pancreatic tumors.

Malignant pancreatic tumors in childhood and adolescence   

Pancreatic tumors in childhood

Pancreatic carcinoma in childhood. Report of an autopsy case and a review of the literature.

Primary pancreatic carcinoma in childhood. Pancreatoblastoma.

Adenocarcinoma of the pancreas of childhood

Pancreatic carcinoma in childhood. Report of an autopsy case and a review of the literature.

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

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