Pancreatic Pathology Online

Focal lymphoid hyperplasia (Pseudolymphoma) of the Pancreas

A rare benign condition of the Pancreas

 

Dr Sampurna Roy MD             July 2016

 

Localized lymphoid hyperplasia of the pancreas is rarely reported and is often indistinguishable from pancreatic neoplasms both clinically or radiographically.

Focal lymphoid hyperplasia (Pseudolymphoma) of the pancreas is characterized by hyperplastic follicles with germinal center and mixed infiltration of plasma cells and mature lymphocytes with no significant cytologic atypia.

The immunostaining show polyclonal origin of the lymphoplasmocytic component.

This lesion should not be mistaken for nodular malignant lymphoma.

Malignant transformation of pseudolymphoma has been reported. It is extremely rare in pancreas.

Castleman's disease of the pancreas is a very rare condition that may resemble more common disease entities as well as pancreatic cancer.

Radical pancreatic resection is usually not performed for localized lymphoid hyperplasia of the pancreas (Pseudolymphoma).

 

Further reading

Pseudolymphoma of the pancreas mimicking cancer.

Reactive lymphoid hyperplasia of the pancreas: a clinical conundrum.

Imaging Findings of Localized Lymphoid Hyperplasia of the Pancreas: a Case Report

Castleman's disease in the head of the pancreas: report of a rare clinical entity and current perspective on diagnosis, treatment, and outcome

Localized lymphoid hyperplasia (pseudolymphoma) of the pancreas presenting with obstructive jaundice.

Reactive lymphoid hyperplasia of the liver and pancreas. A report of two cases and a comprehensive review of the literature.

 

 

Dr Sampurna Roy  MD

Consultant  Histopathologist (Kolkata - India)


 

 

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