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Cellular
neurothekeoma on the left auricle. J Eur Acad Dermatol Venereol.2000
Jul;14(4):314-5
Neurothekeoma
(peripheral nerve sheath myxoma) of the external auditory canal.J
Otolaryngol.1989 Apr;18(3):90-3.
A patient
who presented with an isolated soft-tissue tumor in the lateral
portion of the external auditory canal, which after removal was
diagnosed histopathologically as a peripheral nerve sheath
neurothekeoma, is presented. Peripheral nerve sheath myxomas (neurothekeomas
or perineural myxomas) have been reported to occur on the central
area of the face, arms and shoulders. This is the first case in
which a tumor of this type has been reported to develop in the
external auditory canal. The distinguishing histopathological
characteristics and the differential diagnosis of this tumor are
discussed.
Dermal nerve
sheath myxoma. A light and electron microscopic, histochemical and
immunohistochemical study. Cancer.1984 Apr 15;53(8):1752-9.
Two cases
of dermal nerve sheath myxoma have been examined by light and
electron microscopy, and by immunohistochemical and histochemical
methods. The nomenclature of this tumor has been debated, and the
histogenesis unsettled. Light microscopically, the lobulated myxoid
tumors were generally composed of spindle-shaped and stellate tumor
cells in an abundant matrix of mucosubstances. Ultrastructural
features indicated an origin from the peripheral nerve sheath; among
the pertinent findings were a single or duplicated external lamina
investing the cells, desmosome-like junctions, cytoplasmic
microfilaments and myelin figures, and interdigitating cytoplasmic
processes. S-100 protein was demonstrated by means of the
immunoperoxidase technique within both tumors, further supporting
this origin. The histochemical analysis of the mucosubstance showed
the presence of sulphated glucosaminoglycans. The name dermal nerve
sheath myxoma, suggested by Harkin and Reed, is recommended.
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