| Middle
ear adenocarcinoma with intracranial extension. Case report.
J Neurosurg.1999 Mar;90(3):555-8.
Middle ear
adenocarcinoma is a very rare, locally invasive neoplasm assumed to
arise from the middle ear mucosa. Although endolymphatic sac tumor
(aggressive papillary middle ear tumor) and jugulotympanic
paraganglioma may show brain invasion, intracranial extension of
histologically confirmed middle ear adenocarcinoma has not been
previously reported. The authors describe a 53-year-old man who
suffered from otalgia and tinnitus for more than 10 years and from
neurological deficits for 1 year due to a large temporal bone tumor
that invaded the temporal lobe. A combined neurosurgical and
otolaryngological resection was performed. Pathological analysis
revealed a low-grade adenocarcinoma of a mixed epithelial-neuroendocrine
phenotype, which showed a close histological similarity to, and
topographical relationship with, middle ear epithelium. The authors
conclude that middle ear adenocarcinoma belongs to the spectrum of
extracranial tumors that have possible local extension to the brain.
Primary poorly
differentiated adenocarcinoma of the middle ear.
Auris Nasus Larynx. 1994;21(1):59-63.
Adenocarcinoma of
the middle ear is seldom encountered in clinical practice. In the past
20 years, nearly 20 cases of primary adenocarcinoma of the middle ear
have been reported, and most cases of these tumors have been described
without histologic presentation. To our knowledge, only one case of
adenocarcinoma originating in the postoperative middle ear has been
reported. We describe a case of primary poorly differentiated
adenocarcinoma in the middle ear which was surgically treated for
chronic otitis media 50 years ago. Planning diagnostic and therapeutic
procedures in connection with middle ear tumors is also discussed.
Primary adenocarcinoma of the middle ear.Laryngorhinootologie1990
Feb;69(2):77-9.
One case of
primary adenocarcinoma of the middle ear is reported, which developed
from a chronic otitis media. Histological examination established the
diagnosis of adenocarcinoma. Its clinical appearance was benign, being
restricted to the middle ear and tympanic membrane and with no bone
destruction or metastases. Two years after local surgery there was no
evidence of recurrence.
Primary adenocarcinoma of the temporal bone mimicking paragangliomas:
radiographic and clinical recognition.
Otolaryngol Head Neck Surg.1987 Mar;96(3):231-8.
Three cases of
primary adenocarcinoma of the temporal bone which simulated a glomus
jugulare tumor (on the basis of a thorough preoperative evaluation)
are detailed. In each case, a vascular mass was seen beneath an intact
tympanic membrane and angiography revealed the presence of a highly
vascular mass centered on the jugular bulb. Computed tomography
revealed erosive changes within the jugular fossa that were
characteristic of a glomus jugulare tumor; in two cases, a significant
posterior fossa extension was documented. The intraoperative findings
failed to suggest a lesion different from paraganglioma in two of the
cases; in the remaining case, the erosion of both bone and dura was
diffuse and more suggestive of a malignant neoplasm. A discussion of
the clinical behavior of adenocarcinomas of the middle ear is included
in order to emphasize the importance of differentiating these lesions
preoperatively from the more commonly encountered paragangliomas.
Primary
adenocarcinoma of the middle ear and temporal bone.Arch
Otolaryngol Head Neck Surg. 1987 Aug;113(8):822-4.
Primary
adenocarcinoma of the temporal bone is a rare disorder. Fewer than 40
cases have been reported in the English literature, most of these
being single case reports. Exclusion of metastatic adenocarcinoma is
imperative. Adenocarcinomas must be differentiated from benign
adenomas. Adenocarcinomas are best managed by aggressive surgical
resection, with postoperative irradiation used in cases of incomplete
resection or high-grade tumors.
Primary adenocarcinoma of the middle ear. Arch
Otolaryngol.1975 Nov;101(11):702-5.
Primary
adenocarcinoma of the middle ear is rare. It may or may not be
associated with chronic suppurative otitis media. After the exclusion
of a primary site elsewhere, the tumor should be managed by surgery
and postoperative radiotherapy, especially if tumor excision is
incomplete. We report a case in which primary papillary adenocarcinoma
developed in the middle ear, possibly due to aberrant ceruminous gland
elements. The findings prior to histologic examination were unusual in
that they were consistent with a tumor of the glomus tympanicum or
glomus jugulare.
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