HISTOPATHOLOGY INDIA.COM Atypical Fibroxanthoma
 


                

An approach to reporting of pancreatic specimen ; Reporting of pancreatic biopsies for the diagnosis of neoplastic lesions ; Reporting of ampullary and periampullary biopsies for the diagnosis of neoplastic lesions ; Reporting of Pancreaticoduodenectomy (Whipple's operation) specimen

Distal Pancreatectomy is usually carried out for endocrine tumours and for exocrine neoplasms that arise in the body and tail of the pancreas.

 Nesidioblastosis may be found on a partial pancreatectomy specimens taken for a suspected Insulinoma , and may be inapparent  macroscopically.

Some insulinomas are very small and the entire specimen may need to be embedded in order to find the tumour.

                   

Microscopic report:

The report should comment on :

 - The tumour type:  endocrine, adenocarcinoma, cystadenocarcinoma, cystadenoma ;

 - Perineural and vascular invasion;

 - Extrapancreatic structures involved:  spleen, lymph nodes;

 - Completeness of excision.

For endocrine neoplasms the report should also state the:

 - Pattern of growth: trabecular, moire silk, packeted, diffuse ;

 - Immunostaining characteristics ;

 - Appearance of islets away from the tumour :  hyperplasia, amyloid deposition.  

Anatomy of Normal Pancreas ;Normal Islets of Langerhans ; The Apud Concept ;  Developmental Defects of Pancreas ; Nesidioblastosis ; Pancreas Divisum ; Aberrant(Ectopic) Pancreas ; Annular Pancreas ; Pancreatic Agenesis ; Non-Neoplastic Pancreatic Cysts  ; Pancreatitis ; Acute Pancreatitis ; Chronic Pancreatitis ; Autoimmune Pancreatitis ; Herpes Simplex Pancreatitis ; Diabetes Mellitus ; Neoplasms of the Endocrine Tumours ; Islet Cell Tumours ; Glucagonomas  ; Insulinomas  ; Somatostatinoma ; VIPomas ; Pancreatic Polypeptide-Secreting Tumours ; Enterochromaffin Cell (Carcinoid) Tumours Corticotropinoma ; Multiple Endocrine Neoplasia (MEN) Syndrome ;Non-Neoplastic Pancreatic Cysts including Congenital and Pseudocysts ; Non-Neoplastic Tumour-Like Lesions (Pseudotumour) of the Pancreas ; Focal Lymphoid Hyperplasia(Pseudolymphoma) ; Inflammatory Pseudotumour (Inflammatory Myofibroblastic Tumour); Pyloric Gland Adenoma ;Carcinoma of the Pancreas ;Contrasting histopathological features of obstructed pancreas and pancreatic adenocarcinoma ; Exocrine Pancreatic Tumours ; Paediatric Pancreatic Tumours ; Ductal Adenocarcinoma ; Pancreatoblastoma ; Intraductal Papillary Mucinous Tumour ; Mucinous Cystic Tumours; Serous Cystic Tumours ;Mucinous Non-Cystic and Signet-Ring Cell Carcinoma ;Solid Pseudopapillary Tumour.

 
September 2009

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