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Cutaneous deposition diseases. Part I.J
Am Acad Dermatol. 1998 Aug;39(2 Pt 1):149-71; quiz 172-4. Review.
Erratum in: J Am Acad Dermatol 1998 Dec;39(6):1042.
The cutaneous deposition disorders are a group of unrelated conditions
characterized by the presence of either endogenous or exogenous substances
within the dermis or the subcutis. Part I of this two-part series will
focus on metabolic processes involved in the endogenous deposition in the
various forms of amyloidosis, porphyria, colloid milium, and lipoid
proteinosis. We will also review the clinical, histologic, biochemical,
and ultrastructural findings relevant to each disorder. Basic mechanisms
of pathogenesis, diagnostic modalities, and treatment options are also
discussed. |