A case of Goldenhar's Syndrome (oculoauriculovertebral dysplasia) in a 3-day-old Nigerian neonate with right anophthalmos and lipodermoid, left limbal dermoid, bilateral preauricular appendages and mandibular hypoplasia is presented. The lipodermoid was attached to the tarsal conjunctiva of the lower lid of the anophthalmic side. The causative factor was presumably maternal drug (traditional medicine) ingestion at three months gestation. No similar case has been reported previously. The literature on Goldenhar's Syndrome is briefly reviewed.

A caruncular dermoid with contiguous eyelid involvement: embryologic implications. Ophthal Plast Reconstr Surg. 1998 Sep;14(5):375-7.

An 11-year-old girl with a mass arising from the caruncle and the upper eyelid was examined for spontaneous epibulbar bleeding. Excision of the lesion involved reconstruction of the proximal nasolacrimal system, lid margin, and conjunctiva. The histopathologic diagnosis was consistent with a dermoid of the caruncle. This case is notable not only for a dermoid accompanied by epibulbar bleeding but for its caruncular origin and attachment to the upper eyelid. This case suggests that the caruncle and the upper eyelid arise from similar embryologic structures.

Epibulbar choristomas containing lacrimal tissue. Clinical distinction from dermoids and histologic evidence of an origin from the palpebral lobe. Ophthalmology. 1987 Oct;94(10):1249-57.

Three new cases of epibulbar choristomas, all containing lacrimal tissue, are presented and compared with those reported previously in the literature. The first and second cases were unilateral, complex choristomas, consisting of ectopic lacrimal tissue, smooth muscle, and cartilage; the first case was also remarkable for the presence of lesional tissue in the peripheral cornea and evidence of progressive growth during puberty. The third case was a bilateral, complex choristoma, manifesting epibulbar lacrimal tissue, cartilage, and smooth muscle; also associated were bilateral optic nervehead colobomas and a uniocular focus of posterior scleral cartilage demonstrated by computed tomography (CT) scanning. On clinical examination, all three lesions displayed highly vascularized thickenings of the conjunctiva with diagnostically useful gelatinous elevations, which corresponded microscopically to lobules of lacrimal tissue. In addition, all three cases had the interesting diagnostic feature of superficial corneal scarring or sclerosis, with a fine vascularity adjacent to the conjunctival lesional tissue. Electron microscopy of the third case demonstrated completely normal cytoarchitecture of the lacrimal tissue. Because of the frequent presence of Müller's smooth muscle in epibulbar lacrimal choristomas, the authors propose that these lesions represent embryologic ectopias or overly extensive field effects of the palpebral lobe of the lacrimal gland.

Transconjunctival resection of an orbital dermoid tumour.J Maxillofac Surg. 1985 Oct;13(5):239-42.

An unusual case of an orbital dermoid tumour containing a well differentiated tooth-like structure is documented. A previously unreported surgical approach to a maxillofacial dermoid tumour is introduced. Using a conjunctival incision, orbital floor exploration was undertaken with excellent visibility and access. A large dermoid tumour was removed without the need for an external skin incision. The surgical approach and pathology of this unusual lesion are reviewed.

Ring dermoid syndrome. A new syndrome of autosomal dominantly inherited, bilateral, annular limbal dermoids with corneal and conjunctival extension.Arch Ophthalmol. 1980 Jun;98(6):1059-61.

A new hereditary syndrome of bilateral ocular dermoids is described in five patients from three generations of a single family. There were no associated extraocular anomalies. The choristomas involved the limbus for 360 degrees, extended anteriorly onto the cornea, and extended posteriorly about 5 mm within the conjunctiva for 360 degrees. Additional clinical findings of diagnostic value were conjunctival plaques of keratinization, hairs, and corneal lipid deposition. An irregular corneal astigmatism, amblyopia, and concomitant strabismus were secondary features. The unique bilateral, annular configuration of the dermoids is pathognomonic of this syndrome. Early surgical intervention is indicated to try to improve the visual prognosis and cosmesis. At surgery, the conjunctival portion of one case was easily resected in toto, but the limbal portion required partial excision. Histopathological examination confirmed the clinical diagnosis of dermoid choristoma.