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Virus-induced
chalazion. Eye. 2006 Feb;20(2):242-6
PURPOSE: To
investigate a viral etiology in certain chalazia. METHODS: A
prospective study over 7.5 years of all newly presenting chalazia
associated with diffuse follicular conjunctivitis but without any
other aetiological factors. Patients were investigated for ocular or
systemic infections by history, physical exam, slit-lamp exam,
and/or histology of conjunctival biopsy (including transmission
electron microscopy). RESULTS: A total of 27 patients developed
follicular conjunctivitis without meibomian gland dysfunction,
blepharitis, or sexually transmitted diseases. Evidence for a viral
aetiology included: recent systemic viral illness (15/27), recent
contact with subjects with chalazia or follicular conjunctivitis
(5/27), preauricular lymphadenopathy (4/27), viral corneal disease
(4/27), or viral particles by ultrastructure (4/4). CONCLUSIONS:
Chalazia may be associated with viral conjunctivitis. Intralesional
corticosteroids should be considered with great caution for
viral-induced chalazia.
Cytopathology of
chalazia. Diag Cytopathol 2004 Aug;31(2):118-22
Chalazion is
a common inflammatory condition of the eyelid, usually treated on
the basis of clinical diagnosis alone. Preoperative exclusion of
malignancy in chalazia with atypical clinical presentation could
prevent unwarranted surgery. This is a retrospective study of
aspirates from 16 patients with chalazia having an atypical clinical
presentation. Smears were stained with May-Grunwald Giemsa. Two
broad patterns of granulomatous inflammation reflecting the spectrum
of changes in the course of the disease were seen. Nine smears had
mixed-cell granulomas consisting of neutrophils, lymphocytes, plasma
cells, macrophages, giant cells, and granulation tissue. Seven
smears had suppurating granulomas characterized by epithelioid cell
granulomas with numerous neutrophils in a proteinaceous background.
Fine-needle aspiration cytology of chalazia with atypical clinical
presentation provides a rapid, safe, and reliable means of
documenting the diagnosis and excluding malignancy.
Chalazion
mimicking an eyelid tumor.J Fr Ophtalmol.2004 Feb;27(2):202-5
A 3-year-old
girl had a tumor growing for a month on the superior right eyelid,
attached on the free margin of the eyelid and partially necrotic. A
surgical excision was performed under general anesthesia. The
histopathological study found an inflammatory lesion with
epithelioid and giant cells, evidence of a granuloma, suggesting the
diagnosis of chalazion. This case shows the various clinical
presentations of this common and benign disease of the eyelid.
Pseudotumoral
eyelid inflammation. Apropos of an anatomo-clinical case.J Fr
Ophtalmol.2003 Apr;26(4):423-6
A
clinicopathological case of a 76-year-old male patient with a
chronic inflammatory change of the inferior left eyelid is reported.
The inflammation appeared as a reddish area of the inner part of the
eyelid, without sharp limits, but with loss of lashes. Numerous
local treatments did not to cure this condition. As some true eyelid
tumors may mimic an inflammation during growth and, for example,
sebaceous carcinoma may clinically present as chronic unilateral
blepharitis, a surgical excisional biopsy was performed on this left
eyelid. Its histopathological study showed a granulomatous
inflammation, which was typical of a simple chalazion. This case
clearly illustrates that the chalazion may not always appear as a
limited nodular inflammation of the eyelid, but may have a more
diffuse clinical presentation.
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