Intraductal Papillary Mucinous Tumour of the Pancreas
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The tumors show
papillary proliferations of columnar mucus-secreting epithelial cells replacing the normal duct epithelium. Benign intraductal papillary mucinous adenomas show a simple papillary or villous growth pattern and there is no cellular atypia. Borderline variants show an irregular papillary growth with moderate epithelial dysplasia and frequent mitoses. In intraduct papillary mucinous carcinoma the papillary proliferations show marked irregularity, cribriform gland formation, and marked nuclear abnormalities. |
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