HISTOPATHOLOGY INDIA.COM

       Myxoid Tumours of Soft Tissue


 

Eye Pathology Online
                 

         

Eye ball consists of three layers:

1. External layer-Sclera ;

2. Middle layer-Choroid ;

3. Innermost layer-Retina ;

Sclera: Consists of dense fibroelastic tissue and varies in thickness, being thickest posteriorly and thinnest at the corneal equator of the globe. Sclera is penetrated by the optic nerve and blood vessels.

Uvea (choroid , ciliary body, iris):

  (i) Choroid: Choroid consists of vascular connective layer with heavily pigmented melanocytes and lies between sclera externally and retina internally.

  (ii) Ciliary body: Ciliary body is the forward continuation of the choroid layer bulging into the eye and is attached to the cornea by suspensory ligament. Ciliary body continuously produces aqueous humor, which circulates into the anterior chamber via pupil to be reabsorbed into the canal of Schlemm. Balanced rates of secretion and reabsorption of aqueous humor maintains a constant intra-ocular pressure, which stabilizes the lens and cornea.

 (iii) Iris: Iris is the most anterior part of uvea forming diaphragm in front of the lens. It consists of myoepithelial cells (dilator pupillae) supplied by sympathetic nervous system and smooth muscle fibres (constrictor pupillae) supplied by parasympathetic nervous system. Colour of the iris depends on the amount of pigment in the connective tissue stroma. Blue eyes contain little stromal pigment whereas brown eyes have much stromal pigment. Image

Retina:

Retina is the photosensitive layer terminating behind the ciliary body and consisting of neurons arranged in distinct layers.

The outer most layer of retina is composed of pigmented epithelial cells.

Photoreceptor cells (rods and cones) forms the second layer.

The rod cells (outer segment) contains photoprotein, rhodopsin.

Sharp, clear, ‘straight-ahead’ vision is processed by the macula, which is the central part of the retina.

The pit or depression within the macula, called the fovea, provides the greatest visual acuity.

The choroid layer contains blood vessels that nourish the retina.

Bruch’s membrane provides support to the retina.

 The retinal pigmented epithelium (RPE) protects and nourishes the retina, removes waste products, and prevents new blood vessels from growing into the retina.

Afferent nerve fibres from the retina converge to form the optic nerve.

Cones are similar in basic structure of rods, contain pigments similar to rhodopsin, receptive to blue, green and red light, and the mechanism of transduction is also similar.  Image

             

Conjunctiva:

Conjunctiva is the epithelium which covers the exposed part of the sclera and inner surface of the eyelids.

It is composed of stratified squamous epthelium with goblet cells in the surface layer.

The conjunctival mucous secretions act as the protective layer on the exposed surface of the eye.

 

Eyelid:

Each eyelids consists of fibroelastic plate , the tarsus covered externally by thin, highly folded skin and internally by smooth conjunctiva. The skin contains hair follicles, Meibomian gland, glands of Zeis (modified sebaceous glands), and glands of Moll (modified apocrine sweat glands). Glands of eyelid produce an oily layer, which covers the tear layer preventing evaporation of the tears.

Skeletal muscle, orbicularis oculi (and levator palpibrae in the upper eyelids) represents a forward continuation of the sub-aponeurotic layer of the scalp.

Blood or inflammatory exudates collecting above the scalp aponeurosis may track forward causing marked swelling of the eyelid. Image

Cornea:

The cornea is the thick, transparent portion of the sclero-corneal layer enclosing the anterior one-sixth of the eye.

It is vascular and consists of five layers.

From outside inwards:

(i) Stratified squamous epithelium,

(ii) Bowman’s membrane (basement membrane),

(iii) Substantia propria (collagenous connective tissue forming thin lamellae),

(iv) Descemet’s membrane (thick elastic basement membrane), and

(v) Endothelium lining the inner surface of cornea.

Lacrimal gland : Image1 ; Image2

Lacrimal gland secretes tears, a watery fluid containing antibacterial enzyme lysozyme and electrolytes. Each gland drains into the superior fornix and tears drain to the inner aspect of the eye and then into the nasal cavity via the nasolacrimal duct.

Related External Link : click1  ; click2 .   Visit:  Retinoblastoma

 February 2007
Surgical-Pathology.com

Cardiac Path Online;

Pulmonary Pathology Online

Pathology Quiz Online;

Dermpath-India;

GI Path Online

Mesothelioma-Online;

Soft Tissue Pathology;

Infectious Disease Online; INDEX: A-D ; INDEX: E-L ; INDEX: M-P INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

Pathology of the Eyelid

Reporting of biopsies taken from lesions of the Eyelid

Dermoid cyst of eyelid

Retinoblastoma

Tumour and tumour-like lesions of the Eyelid

Adnexal Tumours of the eyelid;

Epidermal tumours of the Eyelid ;

Melanocytic tumours of the Eyelid ;

Mesenchymal Tumours of the Eyelid ;

Xanthelasma;

Macular Degeneration

Inflammatory diseases of the Eyelid

Chalazion

Pseudorheumatoid nodule (deep granuloma annulare )

Necrobiotic Xanthogranuloma with paraproteinemia

Silica granuloma of the eyelid

Sarcoidosis

Leishmaniasis

Paracoccidioidomycosis

Molluscum Contagiosum

Myxoid Tumours of Soft Tissue

Classification of Soft Tissue Tumour

Gross examination of soft tissue specimen          

A practical approach to histopathological reporting of soft tissue tumours

Grading of soft tissue tumours

Lipomatous tumours

Neural tumours

Myogenic tumours

Fibroblastic/ Myofibroblastic tumours

Myofibroblastic tumours

Fibrohistiocytic tumours

ChondroOsseous tumours

Soft TissueTumours of Uncertain Differentiation               

Notochordal Tumour - Chordoma

Extra-adrenal Paraganglioma

Gastrointestinal Stromal Tumour

AIDS: Cutaneous lesion associated with AIDS

AIDS related malignant tumours