Reporting of biopsies of inflammatory and neoplastic lesions of the eyelid

Myxoid Tumours of Soft Tissue

Biopsies are taken from inflammatory conditions, cysts and neoplasms of the eyelids .

Many diagnoses are made clinically without biopsy, but in difficult cases biopsies and small excision specimens of cysts and inflammatory lesions may be necessary.

Biopsies of non-neoplastic conditions are often taken because a neoplasm is suspected. Eg. Hordeolum or stye are very rarely biopsied, but occasionally severe or deep seated infection can mimic invasive carcinoma. Chalazion can also clinically suggest malignancy and are often biopsied. Dermoid Cyst are also sent for histological examination.

A wide range of benign tumour and tumour-like lesions and malignant tumours of the eyelid are biopsied for confirmation of the diagnosis. Tumour and tumour-like lesions of the Eyelid

The request form should include the following information:

- Age and sex ;

- Symptoms ;

- Clinical impression ;

- Family history of eye disease, including melanocytic abnormalities

- History of diseases affecting the eye ( Eg. tuberculosis , sarcoidosis, hyperlipidaemia ) ;

-History of inherited conditions such as von Recklinghausen’s and Sturge-Weber syndromes;

- History of neoplasia at another site ;

-Relevant surgical operation , findings at operation ,extent of surgery performed ;

ASSESSMENT OF THE BIOPSY:

Inflammatory lesion:

- The type and severity of the inflammation:

- specific type of inflamamation: ( Eg: tuberculosis, leprosy , syphilis)

- non-specific inflammation : ( acute, suppurative, follicular, chronic diffuse, granulomatous, lipogranulomatous )

- Specific condition can be diagnosed or suggested: (Eg: Chalazion, infective diseases, Sarcoidosis );

- Other associated features: Eg: fibrosis, calcification.

Reporting of biopsies - Inflammatory Skin Diseases

Cystic lesion:

- Type of cyst - determined by the lining epithelium and presence of skin adnexal structures in close relation to the wall.

- whether there has been rupture or other chronic inflammatory change.

Benign and malignant tumours of the eyelid: (Similar to cutaneous tumours) Examination of the skin specimen

February 2007

Surgical-Pathology.com

Cardiac Path Online;

Pulmonary Pathology Online

Pathology Quiz Online;

Dermpath-India;

GI Path Online

Mesothelioma-Online;

Soft Tissue Pathology;

Infectious Disease Online; INDEX: A-D ; INDEX: E-L ; INDEX: M-P ; INDEX: Q-Z ; FUNGAL DISEASE ; VIRAL DISEASE.

Pathology of the Eyelid

Normal Anatomy and histology of Eye

Dermoid cyst of eyelid

Inflammatory diseases of the Eyelid

Chalazion;

Retinoblastoma;

Tumour and tumour-like lesions of the Eyelid

Adnexal Tumours of the eyelid;

Epidermal tumours of the Eyelid ;

Melanocytic tumours of the Eyelid;

Mesenchymal Tumours of the Eyelid ;

Xanthelasma

Retinoblastoma